CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family cyclin-G-associated kinase isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14976
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O14976
GAK_HUMAN
Homo sapiens
Cyclin-G-associated kinase

PDB Structure

PDB 4C57
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Cyclin G-Associated Kinase (Gak) Trapped in Different Conformations Using Nanobodies.
Chaikuad, A., Keates, T., Vincke, C., Kaufholz, M., Zenn, M., Zimmermann, B., Gutierrez, C., Zhang, R., Hatzos-Skintges, C., Joachimiak, A., Muyldermans, S., Herberg, F.W., Knapp, S., Muller, S.
Biochem.J.