CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Tau tubulin kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q5TCY1
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q5TCY1
TTBK1_HUMAN
Homo sapiens
Tau-tubulin kinase 1

PDB Structure

PDB 4BTM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-Ray Structural Analysis of Tau-Tubulin Kinase 1 and its Interactions with Small Molecular Inhibitors.
Xue, Y., Wan, P.T., Hillertz, P., Schweikart, F., Zhao, Y., Wissler, L., Dekker, N.
Chemmedchem