CATH Domain 4bqmA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family	glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2

Glutaminase.

based on mapping to UniProt Q9UI32

L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

GLSL_HUMAN

Homo sapiens

Glutaminase liver isoform, mitochondrial

PDB Structure

PDB	4BQM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain Ferreira, I.M., Vollmar, M., Krojer, T., Strain-Damerell, C., Froese, S., Coutandin, D., Williams, E., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Dias, S.M.G., Ambrosio, A.L.B., Yue, W.W. To be Published