CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P18031
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P18031
PTN1_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 1

PDB Structure

PDB 4BJO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nitrate in the Active Site of Protein Tyrosine Phosphatase 1B is a Putative Mimetic of the Transition State.
Kenny, P.W., Newman, J., Peat, T.S.
Acta Crystallogr.,Sect.D