CATH Domain 4b95C02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.750	Elongin C; Chain C, domain 1
	1.10.750.10	von Hippel-Lindau disease tumour suppressor, alpha domain

Domain Context

CATH Clusters

Superfamily	von Hippel-Lindau disease tumour suppressor, alpha domain
Functional Family	von Hippel-Lindau disease tumor suppressor

Enzyme Information

UniProtKB Entries (1)

VHL_HUMAN

Homo sapiens

Von Hippel-Lindau disease tumor suppressor

PDB Structure

PDB	4B95
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1Alpha Buckley, D.L., Gustafson, J.L., Van Molle, I., Roth, A.G., Tae, H.S., Gareiss, P.C., Jorgensen, W.L., Ciulli, A., Crews, C.M. Angew.Chem.Int.Ed.Engl.