×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4b84A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P21836
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P21836
ACES_MOUSE
Mus musculus
Acetylcholinesterase

PDB Structure

PDB 4B84
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors.
Andersson, C.D., Forsgren, N., Akfur, C., Allgardsson, A., Berg, L., Engdahl, C., Qian, W., Ekstrom, F.J., Linusson, A.
J.Med.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...