CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

P07900
HS90A_HUMAN
Homo sapiens
Heat shock protein HSP 90-alpha

PDB Structure

PDB 4B7P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nms-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity in Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases.
Fogliatto, G., Gianellini, L.M., Brasca, M.G., Casale, E., Ballinari, D., Ciomei, M., Degrassi, A., De Ponti, A., Germani, M., Guanci, M., Paolucci, M., Polucci, P., Russo, M., Sola, F., Valsasina, B., Visco, C., Zuccotto, F., Donati, D., Felder, E., Pesenti, E., Mantegani, S., Galvani, A., Isacchi, A.
Clin.Cancer Res.