CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.60 | Homeodomain-like |
Domain Context
CATH Clusters
| Superfamily | Homeodomain-like |
| Functional Family | Chromodomain-helicase-DNA-binding protein 2 isoform 1 |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt O14646
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| O14646 |
CHD1_HUMAN
Homo sapiens
Chromodomain-helicase-DNA-binding protein 1
|
PDB Structure
| PDB | 4B4C |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the DNA-Binding Domain of Human Chd1.
To be Published
|