CATH Domain 4abjA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

TRY1_BOVIN

Bos taurus

Cationic trypsin

PDB Structure

PDB	4ABJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations Tischler, M., Nasu, D., Empting, M., Schmelz, S., Heinz, D., Rottmann, P., Kolmar, H., Buntkowsky, G., Tietze, D., Avrutina, O. Angew.Chem.Int.Ed.Engl.