CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.540
Functional Family

Enzyme Information

3.6.1.15
Nucleoside-triphosphate phosphatase.
based on mapping to UniProt Q27893
NTP + H(2)O = NDP + phosphate.
-!- The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria. -!- Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD. -!- The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.

UniProtKB Entries (1)

Q27893
NTP1_TOXGO
Toxoplasma gondii
Nucleoside-triphosphatase 1

PDB Structure

PDB 4A5A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
Krug, U., Zebisch, M., Krauss, M., Straeter, N.
J.Biol.Chem.