CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family D-amino-acid oxidase

Enzyme Information

1.4.3.3
D-amino-acid oxidase.
based on mapping to UniProt P14920
A D-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
-!- Wide specificity for D-amino acids. -!- Also acts on glycine.

UniProtKB Entries (1)

P14920
OXDA_HUMAN
Homo sapiens
D-amino-acid oxidase

PDB Structure

PDB 3ZNP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
Hopkins, S.C., Heffernan, M.L.R., Saraswat, L.D., Bowen, C.A., Melnick, L., Hardy, L.W., Orsini, M.A., Allen, M.S., Koch, P., Spear, K.L., Foglesong, R.J., Soukri, M., Chytil, M., Fang, Q.K., Jones, S.W., Varney, M.A., Panatier, A., Oliet, S.H.R., Pollegioni, L., Piubelli, L., Molla, G., Nardini, M., Large, T.H.
J.Med.Chem.