CATH Classification

Domain Context

CATH Clusters

Superfamily 2-Layer Sandwich
Functional Family Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Enzyme Information

2.7.1.149
1-phosphatidylinositol-5-phosphate 4-kinase.
based on mapping to UniProt P78356
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.

UniProtKB Entries (1)

P78356
PI42B_HUMAN
Homo sapiens
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

PDB Structure

PDB 3X0A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Sumita, K., Lo, Y.H., Takeuchi, K., Senda, M., Kofuji, S., Ikeda, Y., Terakawa, J., Sasaki, M., Yoshino, H., Majd, N., Zheng, Y., Kahoud, E.R., Yokota, T., Emerling, B.M., Asara, J.M., Ishida, T., Locasale, J.W., Daikoku, T., Anastasiou, D., Senda, T., Sasaki, A.T.
Mol.Cell