CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.800 | Phosphatidylinositol Phosphate Kinase II Beta |
|
3.30.800.10 | Phosphatidylinositol Phosphate Kinase II Beta |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol Phosphate Kinase II Beta |
| Functional Family | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
Enzyme Information
| 2.7.1.149 |
1-phosphatidylinositol-5-phosphate 4-kinase.
based on mapping to UniProt P78356
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.
|
UniProtKB Entries (1)
| P78356 |
PI42B_HUMAN
Homo sapiens
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
|
PDB Structure
| PDB | 3X03 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell
|