CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt Q8E9N3
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

Q8E9N3
LEU3_SHEON
Shewanella oneidensis MR-1
3-isopropylmalate dehydrogenase

PDB Structure

PDB 3WZX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution
Hamajima, Y., Nagae, T., Watanabe, N., Kato-Yamada, Y., Imai, T., Kato, C.
To be Published