CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

Enzyme Information

2.3.1.234
N(6)-L-threonylcarbamoyladenine synthase.
based on mapping to UniProt P43122
L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L- threonylcarbamoyladenine(37) in tRNA.
-!- The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg). -!- Formerly EC 2.6.99.4.

UniProtKB Entries (1)

P43122
QRI7_YEAST
Saccharomyces cerevisiae S288C
TRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

PDB Structure

PDB 3WUH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP
Tominaga, T., Kobayashi, K., Ishii, R., Ishitani, R., Nureki, O.
ACTA CRYSTALLOGR.,SECT.F