1 keywords

CATH Domain 3wfgA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Androgen receptor variant

Enzyme Information

UniProtKB Entries (1)

P08235
MCR_HUMAN
Homo sapiens
Mineralocorticoid receptor

PDB Structure

PDB 3WFG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists.
Hasui, T., Ohra, T., Ohyabu, N., Asano, K., Matsui, H., Mizukami, A., Habuka, N., Sogabe, S., Endo, S., Siedem, C.S., Tang, T.P., Gauthier, C., De Meese, L.A., Boyd, S.A., Fukumoto, S.
Bioorg.Med.Chem.