CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P23443
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P23443
KS6B1_HUMAN
Homo sapiens
Ribosomal protein S6 kinase beta-1

PDB Structure

PDB 3WF5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the S6K1 kinase domain in complexes with inhibitors
Niwa, H., Mikuni, J., Sasaki, S., Tomabechi, Y., Honda, K., Ikeda, M., Ohsawa, N., Wakiyama, M., Handa, N., Shirouzu, M., Honma, T., Tanaka, A., Yokoyama, S.
J.Struct.Funct.Genom.