CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.360
Functional Family

Enzyme Information

1.7.1.17
FMN-dependent NADH-azoreductase.
based on mapping to UniProt C0STY1
Anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH.
-!- The enzyme catalyzes the reductive cleavage of an azo bond in aromatic azo compounds to form the corresponding amines. -!- Does not accept NADPH. -!- Cf. EC 1.7.1.6.

UniProtKB Entries (1)

C0STY1
C0STY1_9BACI
Bacillus sp. B29
FMN-dependent NADH-azoreductase

PDB Structure

PDB 3W78
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism.
Yu, J., Ogata, D., Gai, Z., Taguchi, S., Tanaka, I., Ooi, T., Yao, M.
Acta Crystallogr.,Sect.D