CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | 3-oxoacyl-[acyl-carrier protein] reductase |
Enzyme Information
| 1.1.1.36 |
Acetoacetyl-CoA reductase.
based on mapping to UniProt P14697
(R)-3-hydroxyacyl-CoA + NADP(+) = 3-oxoacyl-CoA + NADPH.
|
UniProtKB Entries (1)
| P14697 |
PHAB_CUPNH
Cupriavidus necator H16
Acetoacetyl-CoA reductase
|
PDB Structure
| PDB | 3VZP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics
Appl.Environ.Microbiol.
|