CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P06150
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P06150
LDH_THECA
Thermus caldophilus
L-lactate dehydrogenase

PDB Structure

PDB 3VPH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
Ikehara, Y., Arai, K., Furukawa, N., Ohno, T., Miyake, T., Fushinobu, S., Nakajima, M., Miyanaga, A., Taguchi, H.
J.Biol.Chem.