CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family Beta-lactamase

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P9WKD3
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P9WKD3
BLAC_MYCTU
Mycobacterium tuberculosis H37Rv
Beta-lactamase

PDB Structure

PDB 3VFF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
BlaC-Specific Fluorogenic Probes for Rapid Tuberculosis Detection
Xie, H., Mire, J.A., Kong, Y., Chang, M., Sacchettini, J.C., Cirillo, J.D., Rao, J.
To be Published