CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.7.1.8
2,6-dioxo-6-phenylhexa-3-enoate hydrolase.
based on mapping to UniProt P47229
2,6-dioxo-6-phenylhexa-3-enoate + H(2)O = benzoate + 2-oxopent-4-enoate.
-!- Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 by ring-fission at a -CO-C bond. -!- Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.

UniProtKB Entries (1)

P47229
BPHD_PARXL
Paraburkholderia xenovorans LB400
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase

PDB Structure

PDB 3V1N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad.
Ruzzini, A.C., Ghosh, S., Horsman, G.P., Foster, L.J., Bolin, J.T., Eltis, L.D.
J.Am.Chem.Soc.