1 keywords

CATH Domain 3uqaA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.10 Roll
Topology 3.10.20 Ubiquitin-like (UB roll)
Homologous Superfamily 3.10.20.90 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Ubiquitin-like protein SMT3

Enzyme Information

UniProtKB Entries (2)

Q63J95
Q63J95_BURPS
Burkholderia pseudomallei K96243
Peptidyl-prolyl cis-trans isomerase
Q12306
SMT3_YEAST
Saccharomyces cerevisiae S288C
Ubiquitin-like protein SMT3

PDB Structure

PDB 3UQA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Begley, D.W., Fox, D., Jenner, D., Juli, C., Pierce, P.G., Abendroth, J., Muruthi, M., Safford, K., Anderson, V., Atkins, K., Barnes, S.R., Moen, S.O., Raymond, A.C., Stacy, R., Myler, P.J., Staker, B.L., Harmer, N.J., Norville, I.H., Holzgrabe, U., Sarkar-Tyson, M., Edwards, T.E., Lorimer, D.D.
Antimicrob.Agents Chemother.