CATH Domain 3uo9B02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family	glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2

Glutaminase.

based on mapping to UniProt O94925

L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

GLSK_HUMAN

Homo sapiens

Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB	3UO9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Full-length human glutaminase in complex with an allosteric inhibitor. DeLaBarre, B., Gross, S., Fang, C., Gao, Y., Jha, A., Jiang, F., Song J, J., Wei, W., Hurov, J.B. Biochemistry