CATH Classification

Domain Context

CATH Clusters

Superfamily Enolase-like, N-terminal domain
Functional Family Enolase

Enzyme Information

4.2.1.11
Phosphopyruvate hydratase.
based on mapping to UniProt P09104
2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
-!- Also acts on 3-phospho-D-erythronate.

UniProtKB Entries (1)

P09104
ENOG_HUMAN
Homo sapiens
Gamma-enolase

PDB Structure

PDB 3UJE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
Qin, J., Chai, G., Brewer, J.M., Lovelace, L.L., Lebioda, L.
J.Inorg.Biochem.