CATH Domain 3uicA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Enoyl-[acyl-carrier-protein] reductase [NADH]

Enzyme Information

UniProtKB Entries (1)

Q5NGQ3_FRATT

Francisella tularensis subsp. tularensis SCHU S4

Enoyl-[acyl-carrier-protein] reductase [NADH]

PDB Structure

PDB	3UIC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and enzymatic analyses reveal the binding mode of a novel series of Francisella tularensis enoyl reductase (FabI) inhibitors. Mehboob, S., Hevener, K.E., Truong, K., Boci, T., Santarsiero, B.D., Johnson, M.E. J.Med.Chem.