CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10140 | Toll/interleukin-1 receptor homology (TIR) domain |
Domain Context
CATH Clusters
| Superfamily | Toll/interleukin-1 receptor homology (TIR) domain |
| Functional Family | Toll/interleukin-1 receptor domain-containing adapter protein |
Enzyme Information
UniProtKB Entries (1)
| P58753 |
TIRAP_HUMAN
Homo sapiens
Toll/interleukin-1 receptor domain-containing adapter protein
|
PDB Structure
| PDB | 3UB4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling
Plos One
|