CATH Domain 3tsyA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.12780	N-terminal domain of ligase-like

Domain Context

CATH Clusters

Superfamily	N-terminal domain of ligase-like
Functional Family	Long-chain-fatty-acid--CoA ligase FadD

Enzyme Information

6.2.1.12

4-coumarate--CoA ligase.

based on mapping to UniProt Q42524

ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.

UniProtKB Entries (2)

Q2HY10	Q2HY10_VITVI Vitis vinifera Resveratrol synthase
Q42524	4CL1_ARATH Arabidopsis thaliana 4-coumarate--CoA ligase 1

PDB Structure

PDB	3TSY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Kinetic Analysis of the Unnatural Fusion Protein 4-Coumaroyl-CoA Ligase::Stilbene Synthase. Wang, Y., Yi, H., Wang, M., Yu, O., Jez, J.M. J.Am.Chem.Soc.