CATH Domain 3tl2A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

Enzyme Information

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt Q6HSF4

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

MDH_BACAN

Bacillus anthracis

Malate dehydrogenase

PDB Structure

PDB	3TL2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation. Blus, B.J., Chruszcz, M., Tkaczuk, K.L., Osinski, T., Cymborowski, M., Kudritska, M., Grimshaw, S., Savchenko, A., Anderson, W.F., Minor, W. TO BE PUBLISHED