CATH Classification

Domain Context

CATH Clusters

Superfamily Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain
Functional Family 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Enzyme Information

2.3.1.117
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.
based on mapping to UniProt P56220
Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
-!- Involved in the biosynthesis of lysine in bacteria, cyanobacteria and higher plants. -!- Earlier erroneously called 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase.

UniProtKB Entries (1)

P56220
DAPD_UNKP
unidentified prokaryotic organism
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

PDB Structure

PDB 3TDT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The conformational change and active site structure of tetrahydrodipicolinate N-succinyltransferase.
Beaman, T.W., Blanchard, J.S., Roderick, S.L.
Biochemistry