CATH Classification

Domain Context

CATH Clusters

Superfamily 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Enzyme Information

4.6.1.12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
based on mapping to UniProt Q8ZMF7
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q8ZMF7
ISPF_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB Structure

PDB 3T80
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine
Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L., Edwards, T.E.
To be Published