CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.250.1180
Functional Family

Enzyme Information

4.1.2.13
Fructose-bisphosphate aldolase.
based on mapping to UniProt B1YAL1
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
-!- Also acts on (3S,4R)-ketose 1-phosphates. -!- The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc. -!- Formerly EC 4.1.2.7.
3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt B1YAL1
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

B1YAL1
FBPAP_PYRNV
Pyrobaculum neutrophilum V24Sta
Fructose-1,6-bisphosphate aldolase/phosphatase

PDB Structure

PDB 3T2C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Du, J., Say, R.F., Lu, W., Fuchs, G., Einsle, O.
Nature