CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family

Enzyme Information

4.2.1.94
Scytalone dehydratase.
based on mapping to UniProt P56221
Scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.
-!- Involved with EC 1.1.1.252 in the biosynthesis of melanin in pathogenic fungi.

UniProtKB Entries (1)

P56221
SCYD_MAGO7
Pyricularia oryzae 70-15
Scytalone dehydratase

PDB Structure

PDB 3STD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site.
Chen, J.M., Xu, S.L., Wawrzak, Z., Basarab, G.S., Jordan, D.B.
Biochemistry