CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic domain N
Functional Family

Enzyme Information

7.2.2.9
P-type Cu(2+) transporter.
based on mapping to UniProt O30085
ATP + H(2)O + Cu(2+)(Side 1) = ADP + phosphate + Cu(2+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell. -!- Formerly EC 3.6.3.4.

UniProtKB Entries (1)

O30085
COPB_ARCFU
Archaeoglobus fulgidus DSM 4304
Copper-exporting P-type ATPase B

PDB Structure

PDB 3SKY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformations of the apo-, substrate-bound and phosphate-bound ATP-binding domain of the Cu(II) ATPase CopB illustrate coupling of domain movement to the catalytic cycle.
Jayakanthan, S., Roberts, S.A., Weichsel, A., Arguello, J.M., McEvoy, M.M.
Biosci.Rep.