CATH Domain 3sfyA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.120	Protein prenylyltransferase

Domain Context

CATH Clusters

Superfamily	Protein prenylyltransferase
Functional Family	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Enzyme Information

UniProtKB Entries (1)

Q55QV6_CRYNB

Cryptococcus neoformans var. neoformans B-3501A

Protein farnesyltransferase subunit beta

PDB Structure

PDB	3SFY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. Hast, M.A., Nichols, C.B., Armstrong, S.M., Kelly, S.M., Hellinga, H.W., Alspaugh, J.A., Beese, L.S. J.Biol.Chem.