CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.357 | Tetracycline Repressor; domain 2 |
|
1.10.357.10 | Tetracycline Repressor, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Tetracycline Repressor, domain 2 |
| Functional Family | HTH-type transcriptional regulator EthR |
Enzyme Information
UniProtKB Entries (1)
| P9WMC1 |
ETHR_MYCTU
Mycobacterium tuberculosis H37Rv
HTH-type transcriptional regulator EthR
|
PDB Structure
| PDB | 3SFI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
J.Med.Chem.
|