CATH Domain 3sfiA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.60	Homeodomain-like

Domain Context

CATH Clusters

Superfamily	Homeodomain-like
Functional Family	TetR family transcriptional regulator

Enzyme Information

UniProtKB Entries (1)

ETHR_MYCTU

Mycobacterium tuberculosis H37Rv

HTH-type transcriptional regulator EthR

PDB Structure

PDB	3SFI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors. Flipo, M., Desroses, M., Lecat-Guillet, N., Villemagne, B., Blondiaux, N., Leroux, F., Piveteau, C., Mathys, V., Flament, M.P., Siepmann, J., Villeret, V., Wohlkonig, A., Wintjens, R., Soror, S.H., Christophe, T., Jeon, H.K., Locht, C., Brodin, P., Deprez, B., Baulard, A.R., Willand, N. J.Med.Chem.