CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.160
Functional Family

Enzyme Information

4.2.3.38
Alpha-bisabolene synthase.
based on mapping to UniProt O81086
(2E,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate.
-!- While unlikely to encounter geranyl diphosphate (GDP) in vivo as it is localized to plastids, the enzyme can use GDP as a substrate in vitro to produce (+)-(4R)-limonene (cf. EC 4.2.3.20). -!- Induced as part of a defense mechanism in the grand fir Abies grandis as a response to stem wounding. -!- Formerly EC 4.2.3.n1.

UniProtKB Entries (1)

O81086
TPSD1_ABIGR
Abies grandis
Alpha-bisabolene synthase

PDB Structure

PDB 3SDU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production.
McAndrew, R.P., Peralta-Yahya, P.P., DeGiovanni, A., Pereira, J.H., Hadi, M.Z., Keasling, J.D., Adams, P.D.
Structure