CATH Classification

Domain Context

CATH Clusters

Superfamily Histone-lysine N-methyltransferase
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q4FZB7
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q4FZB7
KMT5B_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase KMT5B

PDB Structure

PDB 3S8P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Wu, H., Siarheyeva, A., Zeng, H., Lam, R., Dong, A., Wu, X.H., Li, Y., Schapira, M., Vedadi, M., Min, J.
Febs Lett.