CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family Beta-lactamase

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P05364
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P05364
AMPC_ENTCL
Enterobacter cloacae
Beta-lactamase

PDB Structure

PDB 3S4X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of the Asn152Gly mutant of P99 cephalosporinase.
Ruble, J.F., Lefurgy, S.T., Cornish, V.W., Powers, R.A.
Acta Crystallogr.,Sect.D