CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.260 | ACT domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.260 |
| Functional Family |
Enzyme Information
| 2.7.2.4 |
Aspartate kinase.
based on mapping to UniProt P9WPX3
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
-!- The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3. -!- This is also the case for two of the four isoenzymes in Arabidopsis thaliana. -!- The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
|
UniProtKB Entries (1)
| P9WPX3 |
AK_MYCTU
Mycobacterium tuberculosis H37Rv
Aspartokinase
|
PDB Structure
| PDB | 3S1T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
High-resolution X-ray structure of the regulatory domain of the mycobacterial aspartokinase in complex with threonine
To be Published
|