CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.140.2220
Functional Family Histone-lysine N-methyltransferase SMYD3

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H7B4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9H7B4
SMYD3_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SMYD3

PDB Structure

PDB 3RU0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3.
Foreman, K.W., Brown, M., Park, F., Emtage, S., Harriss, J., Das, C., Zhu, L., Crew, A., Arnold, L., Shaaban, S., Tucker, P.
Plos One