CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P18640
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P18640
BXC_CBCP
Clostridium phage c-st
Botulinum neurotoxin type C

PDB Structure

PDB 3R4U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Strotmeier, J., Gu, S., Jutzi, S., Mahrhold, S., Zhou, J., Pich, A., Eichner, T., Bigalke, H., Rummel, A., Jin, R., Binz, T.
Mol.Microbiol.