CATH Classification

Domain Context

CATH Clusters

Superfamily PK beta-barrel domain-like
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q4D9Z4
Q4D9Z4_TRYCC
Trypanosoma cruzi strain CL Brener
Pyruvate kinase

PDB Structure

PDB 3QV9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site.
Morgan, H.P., McNae, I.W., Nowicki, M.W., Zhong, W., Michels, P.A., Auld, D.S., Fothergill-Gilmore, L.A., Walkinshaw, M.D.
J.Biol.Chem.