CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00592
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00592
PA21B_PIG
Sus scrofa
Phospholipase A2, major isoenzyme

PDB Structure

PDB 3QLM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment.
Aparna, V., Dileep, K.V., Mandal, P.K., Karthe, P., Sadasivan, C., Haridas, M.
Chem.Biol.Drug Des.