CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.30.30
Functional Family heat shock 70 kDa protein-like

Enzyme Information

3.6.4.10
Non-chaperonin molecular chaperone ATPase.
based on mapping to UniProt P16474
ATP + H(2)O = ADP + phosphate.
-!- This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. -!- They comprise a number of heat-shock-cognate proteins. -!- They are also active in clathrin uncoating and in the oligomerization of actin.

UniProtKB Entries (1)

P16474
BIP_YEAST
Saccharomyces cerevisiae S288C
Endoplasmic reticulum chaperone BiP

PDB Structure

PDB 3QFU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Yan, M., Li, J., Sha, B.
Biochem.J.