CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Thioredoxin reductase 1, cytoplasmic

Enzyme Information

1.8.1.9
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q16881
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.

UniProtKB Entries (1)

P10599
THIO_HUMAN
Homo sapiens
Thioredoxin

PDB Structure

PDB 3QFA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the human thioredoxin reductase-thioredoxin complex
Fritz-Wolf, K., Kehr, S., Stumpf, M., Rahlfs, S., Becker, K.
Nat Commun