CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family Ketohexokinase

Enzyme Information

2.7.1.3
Ketohexokinase.
based on mapping to UniProt P50053
ATP + D-fructose = ADP + D-fructose 1-phosphate.
-!- D-sorbose, D-agatose and 5-dehydro-D-fructose also act as acceptors.

UniProtKB Entries (1)

P50053
KHK_HUMAN
Homo sapiens
Ketohexokinase

PDB Structure

PDB 3Q92
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.
Maryanoff, B.E., O'Neill, J.C., McComsey, D.F., Yabut, S.C., Luci, D.K., Jordan, A.D., Masucci, J.A., Jones, W.J., Abad, M.C., Gibbs, A.C., Petrounia, I.
ACS Med Chem Lett