CATH Classification

Domain Context

CATH Clusters

Superfamily Arenaviral nucleoprotein, C-terminal domain
Functional Family Nucleoprotein

Enzyme Information

3.1.13.-
Exoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P13699

UniProtKB Entries (1)

P13699
NCAP_LASSJ
Lassa virus Josiah
Nucleoprotein

PDB Structure

PDB 3Q7C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression.
Hastie, K.M., Kimberlin, C.R., Zandonatti, M.A., Macrae, I.J., Saphire, E.O.
Proc.Natl.Acad.Sci.USA