CATH Classification

Domain Context

CATH Clusters

Superfamily SRA-YDG
Functional Family Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt O82175
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

O82175
SUVH5_ARATH
Arabidopsis thaliana
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5

PDB Structure

PDB 3Q0B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Rajakumara, E., Law, J.A., Simanshu, D.K., Voigt, P., Johnson, L.M., Reinberg, D., Patel, D.J., Jacobsen, S.E.
Genes Dev.